Datagrid with editable and non-editable cells

I was wondering how can I create a datagrid with  selectable and non-selectable cells at the same datagrid. There is a condition which will inform if the cell will be selectable or not.  What is the best way to do it? Another problem that I have is when I select one cells and in the datagrid  has just one element it still being selected. I want on the event onkeyup  lose its focus

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